http://hdl.handle.net/10564/1550 2002-04 Fri, 10 Apr 2026 15:39:15 GMT 2026-04-10T15:39:15Z http://hdl.handle.net/10564/70 タイトル: 発作後精神病状態を呈した1例 著者: 宮本, 敏雄; 川崎, 淳; 岸本, 年史 抄録: In epilepsy various psychiatric symptoms occur, such as neurotic symptoms，mood disorder-like symptoms, and schizophrenia-like symptoms. The incidence of psychotic symptoms among epileptic patients is significantly higher than among the general population. Sengoku et al. reported the incidence of psychosis among epileptic patients to be 4.4％. Psychotic disorders associated with epilepsy are divided into three groups: ictal psychosis, periictal psychosis, and interictal psychosis. Altemative psychosis and postictal psychosis are classified as acute periictal and interictal psychosis. We report a case of postictal psychosis and discuss the psychotic state, comparlng it with that of alternative psychosis. This postictal psychosis exhibited various features different from those of altemative psychosis, and many features of these symptoms are similar to those described in other reports. Many studies suggest that postictal psychoses and altemative psychoses have different features from case to case. Postictal psychoses often exhibit abnormally elevated mood and few schizophrenia-like symptoms such as Schneider's first-rank symptoms, whereas alternative psychoses often do exhibit Schneider's first-rank symptoms. This case showed typical features of postictal psychosis. Mon, 29 Apr 2002 15:00:00 GMT http://hdl.handle.net/10564/70 2002-04-29T15:00:00Z http://hdl.handle.net/10564/69 タイトル: くも膜のう胞の合併が疑われたパニック障害の1症例 著者: 武原, 弘典; 森川, 将行; 徳山, 明広; 金, 英浩; 洪, 基朝; 永野, 龍司; 岸本, 年史 抄録: Arachnoid cyst is a benign tumor that is satisfied in cerebrosplnal fluid, and it arises in the subarachnoid cavity. Though it is often asymptOmatic, increased intracranial pressure and convulsive seizure may rarely be combined. We report a rare case of panic disorder where a combination with arachnoid cyst was suspected. The patient (a48-year-old female) was admitted to our psychiatric ward for the treatment of panic disorder. Arachnoid cyst in mega cisterna magna was indicated by brain MRI, and this was thought to be pressing on the cerebellum. She was treated with medication (alprazoram, setiptiline) and behavioral therapy. As a result, her anxiety symptoms gradually improved. Since she had complained of morning headache during hospitalization, this headache might have been induced by the arachnoid cyst. The cyst might have affected panic disorder and careful observation is also required for the future. Mon, 29 Apr 2002 15:00:00 GMT http://hdl.handle.net/10564/69 2002-04-29T15:00:00Z http://hdl.handle.net/10564/68 タイトル: HLA-E,-F,-Gの発現と機能　胎児・母体間免疫のブラックボックスは開きうるか 著者: 石谷, 昭子 抄録: いかなるHLA class IIもHLA-A，-Bも発現していない胎盤トロフォブラスト上には，多型性の乏しいHLA-E，-F，-Gが発現している。これらの分子の相互作用がどのように妊娠の維持に働いているかについて述べる。また最近，HLA-Gがアロ反応性T細胞のアポトージスを誘導する等の免疫寛容に係わっているという報告がでて，移植免疫の分野においても脚光を浴び始めている。これら分子の基礎と最新の知見について考察する。 Mon, 29 Apr 2002 15:00:00 GMT http://hdl.handle.net/10564/68 2002-04-29T15:00:00Z http://hdl.handle.net/10564/67 タイトル: 原発性肺高血圧症の基礎と臨床 著者: 木村, 弘 抄録: 原発性肺高血圧症(Primarypulmonaryhypertension；PPH)は，著しい前毛細血管性肺高血圧症のうち，肺高血圧症の基礎疾患となりうる心肺疾患がなく，原因が不明のものに与えられる臨床診断名である。本症の予後はきわめて不良で，確定診断からの中間生存率は3年以下で，5年生存率も40％前後である。1998年10月に臓器移植法が施行され，わが国においても移植医療が可能となったが，2002年1月の時点で，肺移植レシピエント待機症例41例中の25例がPPHとなっている。このことからも，PPHの重症度および社会的注目度がうかがえる。これまでの優れた基礎研究成果の積み重ねは臨床現場に還元され，PGI2静注薬による持続静注療法に発展した。現在では移植を待つ患者のつなぎ治療法として，その有用性が証明されている。難治性肺高血圧症の正しい診断方法の確立とともに，現状の治療限界を克服するためにも，遺 伝子治療の発展につながりうる病因・発症機序の究明が急がれる。 Mon, 29 Apr 2002 15:00:00 GMT http://hdl.handle.net/10564/67 2002-04-29T15:00:00Z