http://hdl.handle.net/10564/1546 2001-12 Fri, 10 Apr 2026 15:38:38 GMT 2026-04-10T15:38:38Z http://hdl.handle.net/10564/690 タイトル: 第122回奈良医学会 : 学会記事 Sun, 30 Dec 2001 15:00:00 GMT http://hdl.handle.net/10564/690 2001-12-30T15:00:00Z http://hdl.handle.net/10564/689 タイトル: うつ病性昏迷により高ナトリウム血症を呈した1例 著者: 坂井, 康純; 法山, 良信; 森川, 将行; 金, 英浩; 芳野, 浩樹; 大澤, 弘吉; 岸本, 年史; 飯田, 順三 抄録: Hyponatremia is well known to be caused by water intoxication, but there are few reports on hypernatremia induced by mental disorder. We report a rare case of secondary hypernatremia caused by depressive stupor. The patient (a 57-year- old female) refused to eat, drink or speak due to depressive stupor. As a result, she suffered from hypohydremia with hypernatremia (serum sodium 157mEq/l, urea nitrogen 114mg/dl), and was admitted to our psychiatric ward. She was treated with infusion (hypoosmosis) and antidepressants (mainly clomipramine). Her depressive stupor and hypernatremia were gradually improved. Generally, hypernatremia results from water depletion, disturbance of consciousness, or adipsia due to organic brain syndrome. Furthermore, the possibility exists that mental disorder induces secondary hypernatre- mia. In the case of a patient with hypernatremia, secondary influences induced by mental disorder need to be considered. Sun, 30 Dec 2001 15:00:00 GMT http://hdl.handle.net/10564/689 2001-12-30T15:00:00Z http://hdl.handle.net/10564/688 タイトル: 薬物性洞機能不全症候群を発症した老年者陳旧性心筋梗塞の1例 著者: 田中, 賢治; 山野, 繁; 中嶋, 民夫; 橋本, 俊雄 抄録: A case of drug-induced sick sinus syndrome (SSS) in a 60-year-old male with old myocardial infarction is reported. The patient had myocardial infarction in March 1989. He palpitated in August 1998. Paroxysmal supraventricular tachycardia (PSVT) diagnosed by ECG was medicated by disopyramide and procainamide. Then he had syncope attack in October 1998. A sinus arrest for 4.4 seconds was detected on 24- hour Holter ECG. Sinus node recovery time was within normal range after he stopped taking the antiarrhythmic agents. So the patient was diagnosed as having drug-induced SSS. The administration of more than two kinds of antiarrhythmic agents is not certainly safe. Disopyramide and procainamide are reported to have a direct depressant action on normal sinus node cell at the toxic level. In this case the patient had renal dysfunction, so the dose of the antiarrhyttmic agents might be thought to increase to the toxic level. Sun, 30 Dec 2001 15:00:00 GMT http://hdl.handle.net/10564/688 2001-12-30T15:00:00Z http://hdl.handle.net/10564/687 タイトル: 生後ラット三叉神経運動核におけるsrcファミリー蛋白発現の経時的観察 著者: 高山, 賢一; 森本, 佳成; 杉村, 正仁; 山田, 英二; 井上, 和也 抄録: Non-receptor-type tyrosine kinases of the Src family, such as Src, Fyn, and Yes, are broadly expressed in the brain and have been suggested to have an important function in the central nervous system. To clarify the role of Src family tyrosine kinases in the developmental process of neurons in the trigeminal motor nucleus that regulate movement of muscles of mastication, we investigated the expressions of c- Src, Fyn, and c-Yes in the trigeminal motor nucleus in rats during the period of transition from suckling to mastication using immunohistochemistry. c-Src expression began to increase on day 14 after birth, on which weaning was started, and the expression reached its peak on day 18, then gradually decreased. Fyn expression was slightly positive in the nuclei in all groups, and there was no difference in the reaction intensity among the groups. c-Yes expression was strongly positive in the cytoplasm and axon in all groups, and there was no difference in reaction intensity among the groups. The above findings suggest that Src family tyrosine kinases are closely involved in the development of motor neuron in the trigeminal motor nucleus and the development and maintenance of masticatory movement. Sun, 30 Dec 2001 15:00:00 GMT http://hdl.handle.net/10564/687 2001-12-30T15:00:00Z