http://hdl.handle.net/10564/1532 1999-08 Thu, 09 Apr 2026 03:40:28 GMT 2026-04-09T03:40:28Z http://hdl.handle.net/10564/535 タイトル: 敗血症性ショックをきたした糖尿病合併尿路感染症の1例 著者: 上田, 重彦; 安, 辰一; 足立, 聡; 奥, 和美; 高木, 正博; 松本, 昌美; 岸野, 辰樹; 田畑, 尚一 抄録: A 70-year-old woman was admitted to our hospital because of fever and loss of consciousness. She had been quite well until the morning of the admission day, but then developed fever and became drowsy in several hours. On arrival at our hospital, her consciousness was "Ⅱ-10"(by Japan Coma Scale) and physical findings presented an impending shock state including very low blood pressure and oligouria. Laboratory examinations disclosed marked leukocytosis and elevation of C-reactive protein. Urine specimen contained some bacteria, and the culture studies demonstrated the growth of Escherichia coli, from both specimens of arterial blood and urine. We made a diagnosis of septic shock, probably originating in urinary infection. The patient recovered from the shock state in 24 hr during the period of intensive treatments including administration of dopamine and antibiotics "Piperacillin sodium". Repeated culture studies of blood and urine turned to be negative on the third day of the treatment period. No anatomical or physiologi- cal abnormality was demonstrated in the urinary tract. However, high levels of blood glucose and glucosuria were observed during the treatment. Although the glucose level was fairly controlled without any medication except diet therapy, the existence of diabetes mellitus might have been a triggering factor for urinary infection causing uroseptic shock. Mon, 30 Aug 1999 15:00:00 GMT http://hdl.handle.net/10564/535 1999-08-30T15:00:00Z http://hdl.handle.net/10564/534 タイトル: 乳癌の化学療法後に骨髄異形成症候群を発症した高齢者末期腎不全の1例 著者: 濱野, 一將; 山野, 繁; 川野, 貴弘; 椎木, 英夫; 橋本, 俊雄; 土肥, 和紘; 中村, 忍 抄録: A case of chemotherapy-induced myelodysplastic syndrome (MDS) in a 78 -year-old female with pancytopenia is reported. The patient had developed left breast cancer in March 1972. After a mastectomy, she was treated with 5-fluorouracil (5-FU) and mitomycin C without radiotherapy. Mild pancytopenia was detected in January 1998. In April 1998, red cell count was 1,540,000/μl, white cell count was 2,400/μl, and platelet count was 69,000/μl. A bone marrow examination in April 1998 showed normal cellularity with 24% blasts. There were dysplastic changes in the erythroid and granulocyte series, and Auer rods in the cytoplasm. The patient was diagnosed as having therapy-related MDS (RAEB-T). MDS is one of the most serious late complications related to chemotherapy. Although alkylating agents are potentially leukemogenic in patients with therapy related- MDS, in this case MDS developed after treatment with 5-FU and mitomycin C. Mon, 30 Aug 1999 15:00:00 GMT http://hdl.handle.net/10564/534 1999-08-30T15:00:00Z http://hdl.handle.net/10564/533 タイトル: 短期間に急速な直腸浸潤が認められた未治療前立腺癌の1例 著者: 山口, 旭; 田中, 宣道; 明山, 達哉; 上甲, 政徳; 三馬, 省二 抄録: A case with non-treated prostate cancer, which showed rapid rectal involve- ment in 3 months, is reported. A 62-year-old man visited our out-patient clinic for periodic follow-up studies for urolithiasis in, August 1997. In spite of having no symptoms on urination, a Tandem-R (RIA) prostatic specific antigen (PSA) level was 5.8 ng/ml. Although transrectal ultrasonography demonstrated no signs of malignancy, endorectal MR imaging done in November showed a low intensity area of 15 mm in diameter in the right peripheral zone of the prostate. Stage T2 prostate cancer was strongly suspected. At the time of needle biopsy of the prostate done in 3 months, a solid mass was detected on ultrasonography at the posterior, distal side of the prostate, which was clearly distinguished from the prostate. The selectively obtained biopsy specimens from the prostate and the mass were histopathologically diagnosed as poorly differentiated adenocarcinoma. Thick- ening of the rectal wall was recognized in MR imaging. From the findings of recto- sigmoidal colonoscopy and immunohistochemical staining with PSA of both biopsy speci- mens, the rectal mass was judged to be an invasion of prostate cancer. With a combination therapy with maximum androgen blockade and radiation, the tumor was reduced in size and PSA level decreased from 73 ng/ml at the therapy initiation to 0.3 ng/ml. Although prostate cancer, in general, shows slow growth, a prompt diagnosis might be required, even when early prostate cancer is suspected. Mon, 30 Aug 1999 15:00:00 GMT http://hdl.handle.net/10564/533 1999-08-30T15:00:00Z http://hdl.handle.net/10564/532 タイトル: Automated Lamellar Keratoplasty施行後の角膜組織変化 著者: 坂口, 泰久; 名和, 良晃; 魚里, 博; 原, 嘉昭; 西信, 元嗣 抄録: We performed automated lamellar keratoplasty using rabbit eyes. Risks and benefits of microkeratome were explored by examining histopathologicai change of corneas following surgery. In cases with seccessful procedure, corneas were clear and smooth. However, in cases with troubles during surgery, severe scar formation and epithelial downgrowth were observed. Intraoperative warming and cooling had little influence on the outcome of surgery. For successful surgery using microkeratome, develop- ment of a more safe surgical system Is considered to be necessary. Mon, 30 Aug 1999 15:00:00 GMT http://hdl.handle.net/10564/532 1999-08-30T15:00:00Z