http://hdl.handle.net/10564/1947 1991-10 2026-04-10T15:40:10Z http://hdl.handle.net/10564/1963 タイトル: 被服の圧迫による皮膚温の変化に関する研究 著者: 杉本, 弘子; 城, 真理子; 関, 美彦; 山下, 節義 抄録: The effect of clothes-mediated compression on body temperature was examined using thermography. When the trunk was compressed with a compression width of 36 cm and a compression-intensity of 40 mmHg/cm² for 30 minutes, the following results were obtained. (1) The skin temperature at the anterior and posterior aspects of the chest and neck began to increase from 5 minutes after compression and continued to gradually increase with time until 30 minutes. These increases continued even after decompression. (2) The skin temperature of the neck was higher at both anterior and posterior regions than that of the chest. The neck also underwent a higher degree of skin temperature increase by compression. (3) The skin temperature of the lower leg showed no significant changes, but that of the foot gradually decreased by compression. (4) The skin temperature of the palm increased until 15 minutes after compression, but it decreased at 30 minutes to the temperature level before compression. The skin temperature further decreased after decompression. (5) The temperature increased by 0.2℃ at 5 minutes after compression. At 20 minutes, it reached an almost steady state and increased by approximately 0.3℃ from the temperature level before compression. The temperature remained on the same level even 15 minutes after decompression. (6) It was found that the skin temperature increased corresponding to increases in the width and intensity of compression application. 1991-10-30T15:00:00Z http://hdl.handle.net/10564/1962 タイトル: ヒト胃癌のヌードマウスにおける癌性腹膜炎モデルの確立とMitomycin Cによる腫瘍細胞増殖促進効果について 著者: 山田, 義帰; 渡辺, 明彦; 澤田, 秀智; 中谷, 勝紀; 中野, 博重 抄録: Malignant potential of carcinoembryonic antigen (CEA)-producing human gastric adenocarcinoma (NS-8) was studied by intraperitoneal transplantation in nude mice. NS-8 carcinomatous peritonitis model was established by intraperitoneal transplantation of more than 1×10⁵ tumor cells. Pretreatment of MMC (5 mg/kg or 1 mg/kg) in the peritoneal cavity 3 hours before i. p. inoculation of 1×10⁶ tumor cells resulted in enhancement of the malignant potential and increase of plasma CEA level. Posttreatment of MMC in the peritoneal cavity 3 hours after i. p. inoculation of 1×10⁶ tumor cells reduced tumor growth and plasma CEA level. A slight enhancement of the malignant potential was recognized by pretreament of MMC in the peritoneal cavity 3 hours before i. p. inoculation of 1×10⁴ tumor cells. Peritoneal exudate cells (PEC) were decreased by MMC (5 mg/kg) i. p. injection at 3 days. Macrophages of PEC were decreased about 30% by MMC i. p. injection at 3 hours. The peritoneal surface was observed after MMC treatment by scanning electron microscopy (SEM). Microvilli of the peritoneal surface were injured from 24 hours after MMC i. p. injection. These results suggest that immunological supression in the peritoneal cavity and peritoneal surface tissue injury caused by pretreatment of MMC may play an important role in malignant potential. 1991-10-30T15:00:00Z http://hdl.handle.net/10564/1961 タイトル: シェーグレン症候群の心臓障害に関する研究 ： 非観血的方法による検討 著者: 吉田, 和正 抄録: In this study, cardiac involvements in 50 patients with Sjögren's syndrome were observed noninvasively using echocardiography and pulsed Doppler echocardiography and compared with 24 age-matched healthy controls. The results were as follows : (1) Nonspecific ECG abnormalities were found in 22 patients (44%). These abnormalities were not dependent on ANF or anti-SS-A antibody. (2) Systolic ventricular function in patients with Sjögren's syndrome was not significantly different from that in the controls. However, left ventricular wall thickness and left ventricular mass in patients with Sjögren's syndrome were increased compared to those in the controls (p＜0.01). (3) Isovolumic relaxation time (IRT ; from the aortic second heart sound to the opening of the mitral valve) in patients with Sjögren's syndrome (mean 79±16 msec) was significantly different from that in the controls (63±14 msec) (p＜0.01). These findings were partially dependent on duration of disease but not on whether complication, ANF, or anti-SS-A antibody was present. (4) Pericardial effusion was detected in 16 patients with Sjögren's syndrome (32%). (5) Valvular regurgitation was identified in 8 patients (17.0%) with Sjögren's syndrome and in 3 controls (12.5%). These findings suggest that left ventricular diastolic property in patients with Sjögren's syndrome is impaired in comparison with that in the healthy controls. 1991-10-30T15:00:00Z http://hdl.handle.net/10564/1960 タイトル: 奈良県立医科大学および奈良県立奈良病院泌尿器科における副腎疾患手術症例の検討 著者: 仲川, 嘉紀; 大園, 誠一郎; 久門, 俊彦; 吉井, 將人; 三馬, 省二; 植村, 天受; 平尾, 佳彦; 岡島, 英五郎; 影林, 頼明; 新井, 邦彦; 妻谷, 憲一; 金子, 佳照; 佐々木, 憲二; 青山, 秀雄 抄録: A total of 64 patients with adrenal disease underwent surgical treatment at the departments of Urology at Nara Medical University and Nara Prefectural Nara Hospital between August, 1962 and July, 1991. In this study, we examine the usefulness of various image diagnostic methods for accurate preoperative localization of the adrenal lesions. Because of the advance of various image diagnostic methods such as US, CT-scan and MRI, highly accurate preoperative diagnosis and increase of the incidence of incidentaloma were achieved. In addition, current localized diagnosis made surgical invasiveness decreased by facilitating the appropriate choice of approach to adrenal lesions. 1991-10-30T15:00:00Z