2017-12 http://hdl.handle.net/10564/3468 2026-04-10T15:44:09Z 2026-04-10T15:44:09Z http://hdl.handle.net/10564/3473 2018-08-08T16:30:11Z 2017-12-30T15:00:00Z

タイトル: 第137回奈良医学会 : 学会記事

2017-12-30T15:00:00Z Uno, Kenji Kasahara, Kei Kajita, Akihiro Hishiya, Naokuni Imakita, Natsuko Imai, Yuichiro Konishi, Mitsuru Ogawa, Yoshihiko Hirai, Nobuyasu Ogawa, Taku Nakamura-Uchiyama, Fukumi Yonekawa, Shinsuke Hirata, Kazuki Nakai, Tokiko Ohbayashi, Chiho Mikasa, Keiichi http://hdl.handle.net/10564/3472 2018-08-08T16:30:10Z 2017-12-30T15:00:00Z

タイトル: Aortic Dissection in a Patient with Human Immunodeficiency Virus Infection That was Diagnosed at Autopsy : A Case Report. 著者: Uno, Kenji; Kasahara, Kei; Kajita, Akihiro; Hishiya, Naokuni; Imakita, Natsuko; Imai, Yuichiro; Konishi, Mitsuru; Ogawa, Yoshihiko; Hirai, Nobuyasu; Ogawa, Taku; Nakamura-Uchiyama, Fukumi; Yonekawa, Shinsuke; Hirata, Kazuki; Nakai, Tokiko; Ohbayashi, Chiho; Mikasa, Keiichi 抄録: A 43-year-old homosexual man was referred to our hospital for chest pain and loss of consciousness. He was hypertensive, and had an uncontrolled viral load. Serum creatinine revealed acute renal failure, and he died 3 days later. On autopsy, aortic dissection (TypeB) was found. No obvious inflammatory change, granulation, bacterial or fungal infection, or medionecrosis were seen at the dissection site. To our knowledge, this was the first case with HIV in whom aortic dissection was diagnosed at autopsy. Aortic dissection is a potential differential diagnosis even in young patients presenting with hypertension and chest pain.

2017-12-30T15:00:00Z 鶴井, 裕和 大東, 雄一郎 巽, 孝成 森田, 敏裕 蜂須賀, 崇 http://hdl.handle.net/10564/3471 2018-08-07T16:30:09Z 2017-12-30T15:00:00Z

タイトル: 術前MDCT、腹腔鏡による診断、治療が有効であったMeckel憩室炎の一例 著者: 鶴井, 裕和; 大東, 雄一郎; 巽, 孝成; 森田, 敏裕; 蜂須賀, 崇 抄録: A 56-years-old-man was admitted to our hospital because of lower abdominal pain. We found a cystic mass with inflammation 2cm in diameter connected to the small intestine in abdominal MDCT. Laparoscopic surgery was performed after it was diagnosed as Meckel's diverticulitis. With the recent progression in diagnostic imaging and laparoscopic surgery, lesions that had been difficult to detect by imaging in the past have become detectable and be treatable. Diagnosis and treatment of Meckel's diverticulitis with acute abdominal disease is useful for preoperative diagnosis by MDCT and definitive diagnosis and therapy by laparoscopic surgery, and it seems that it will become standard therapy in the future.

2017-12-30T15:00:00Z Kuwada, Masaomi Miyake, Makito Gotoh, Daisuke Tatsumi, Yoshihiro Nakai, Yasushi Anai, Satoshi Chihara, Yoshitomo Hirao, Yoshihiko Haramoto, Masaki Tanaka, Nobumichi Fujimoto, Kiyohide http://hdl.handle.net/10564/3470 2018-08-07T16:30:10Z 2017-12-30T15:00:00Z

タイトル: Pretreatment Platelet-to-Lymphocyte Ratio as Biomarker for Neoadjuvant Chemotherapy Prior to Radical Cystectomy in Muscle-Invasive Bladder Cancer. 著者: Kuwada, Masaomi; Miyake, Makito; Gotoh, Daisuke; Tatsumi, Yoshihiro; Nakai, Yasushi; Anai, Satoshi; Chihara, Yoshitomo; Hirao, Yoshihiko; Haramoto, Masaki; Tanaka, Nobumichi; Fujimoto, Kiyohide 抄録: Objectives : To evaluate the clinical benefit of neoadjuvant chemotherapy with gemcitabine and cisplatin (GC) in patients with muscle-invasive bladder cancer treated with radical cystectomy and to identify patients who may benefit from neoadjuvant chemotherapy and predictors of therapeutic response to it. Methods : In this prospective study, we enrolled 37 patients with muscle-invasive bladder cancer (cT2-4aNanyM0). The primary endpoint was the pathological response rate at cystectomy after receiving neoadjuvant GC chemotherapy. Univariable and multivariable analyses were used to determine predictive factors of pT0N0 and ≦pT1N0. The secondary endpoints were adverse events during chemotherapy, surgical complications, as well as overall, disease-specific, and recurrence-free survival. Results : A mean of 2.7 cycles of neoadjuvant GC was administered. Pathological complete response (pT0N0), partial response (pTisN0/pT1N0), and pathological response (≦pT1N0) rates were 24.3%, 27.0%, and 5l.3%, respectively. Grade 3 or 4 non-hematologic adverse events were rare. Three-year overall, disease-specific, and recurrence-free survival rates were 70.7%, 8l.3%, and 63.9%, respectively. Patients with pathological response (≦pT1N0) demonstrated a significantly improved 3-year overall survival rate (94.7% vs. 42.8%), disease-specific survival rate (94.7% vs.62.9%), and recurrence-free survival rate (80.6% vs.45.5%), compared with pathological non-responders (≦pT2Nany). Clinical stage cT2 and low pre-chemotherapy platelet-to-lymphocyte ratios were significant indicators of favorable pathological response to neoadjuvant Gc. Conclusions : Neoadjuvant chemotherapy using GC is safe and effective in patients with muscle-invasive bladder cancer, Pretreatment clinical T2 stage and low platelet-to-lymphocyte ratios were predictive markers for successful neoadjuvant treatment of muscle-invasive bladder cancer with GC.

2017-12-30T15:00:00Z