1993-10 http://hdl.handle.net/10564/1766 2026-04-10T15:40:45Z 2026-04-10T15:40:45Z 常深, 邦彦 http://hdl.handle.net/10564/1773 2017-05-29T06:07:41Z 1993-10-30T15:00:00Z

タイトル: イヌの膀胱腫瘍における自然史の病理組織学的検討 ： Ⅱ. N-butyl-N-(4-hydroxybutyl)nitrosamineにて発生したイヌの膀胱腫瘍の病理組織学的所見のMappingによる検討 著者: 常深, 邦彦 抄録: Histopathological mapping study was performed on the development and progression of urinary bladder tumor induced by N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) in five adult beagle dogs and four adult mongrel dogs. The results are as follows : 1) Urinary bladder tumors induced by low doses of BBN showed papillary, non-invasive type, G1-2, pTa-1 carcinomas which were similar to human superficial bladder cancer ; 2) Microinvasion was occasionally observed in the papillary, non-invasive tumors induced by low doses of BBN, especially in the proliferated cells with atypia in the lamina propria ; 3) Urinary bladder tumors induced by high doses of BBN showed non-papillary, invasive type, G2-3, pT3b, and carcinoma in situ (CIS), which were similar to human invasive bladder cancer ; 4) No malignant progression was seen in low-grade, low-stage tumors during observation through the whole life of the dogs ; 5) The duration and the total dosage of BBN until bladder tumor occurred in beagle dogs were longer and higher than those of BBN in mongrel dogs ; 6) Those changes such as mild dysplasia and Brunn's nests-like lesion in lamina propria were seen during the development of low grade, papillary and non-invasive bladder tumors induced by low dose of BBN. On the other hand, those changes such as severe dysplasia and carcinoma in situ were seen during the development of non-papillary, invasive transitional cell carcinomas induced by high dose of BBN. The present study suggests that it contributed to knowledge of the natural history of bladder carcinogenesis in dogs, and is a valuable model of bladder carcinoma in humans.

1993-10-30T15:00:00Z 古家, 仁 二永, 英男 平井, 勝治 北口, 勝康 山上, 裕章 謝, 慶一 下川, 充 梁, 宗哲 長畑, 敏弘 橋爪, 圭司 松澤, 伸好 橋本, 道代 榮長, 登志 葛本, 直哉 諸井, 慶七郎 井上, 聡己 菊本, 克郎 田山, 準子 奥田, 孝雄 http://hdl.handle.net/10564/1772 2017-05-29T06:07:38Z 1993-10-30T15:00:00Z

タイトル: 手術患者の手術室入室より手術開始までの所要時間に関与する因子 ： 1992年麻酔科管理症例の検討 著者: 古家, 仁; 二永, 英男; 平井, 勝治; 北口, 勝康; 山上, 裕章; 謝, 慶一; 下川, 充; 梁, 宗哲; 長畑, 敏弘; 橋爪, 圭司; 松澤, 伸好; 橋本, 道代; 榮長, 登志; 葛本, 直哉; 諸井, 慶七郎; 井上, 聡己; 菊本, 克郎; 田山, 準子; 奥田, 孝雄 抄録: The contributing factors which related to the duration of preoperative period in the operating theater of Nara Medical University Hospital are assessed. The 3295 anesthetic records from January 1 to December 31 of 1992 were examined retrospectively. The duration from arrival at the operating room to start of surgery were classified into five groups according to consumed time at intervals of 30 minutes. As the results, average duration was 47.8±22.2 min. In the elective cases, the most frequent subjects, 1889 patients (57%), were classified to 30-60 min group. They were composed of cases in the other departments except for Department of 2nd and 3rd Surgery which were classified to 30-60 min group and the cases of Department of 2nd and 3rd Surgery were classified to 60-90 min group. In the emergency cases, 181 patients (33%) were classified to less than 30 min group. As factors of time-consumption in the preoperative period (more than 90 min), we considered various procedures such as intubation using special endobronchial tube, puncture of central vein and artery, cannulation of Swan-Ganz catheter, epidural puncture, posture change etc. To reduce the duration of the preoperative period, we should reconsider the training curriculum of unexperienced anesthesiologists and keep the teamwork between anesthesiologists, surgeons, and nurses.

1993-10-30T15:00:00Z 古家, 仁 葛本, 直哉 平井, 雅治 北口, 勝康 山上, 裕章 下川, 充 謝, 慶一 梁, 宗哲 長畑, 敏弘 橋爪, 圭司 松澤, 伸好 橋本, 道代 榮長, 登志 二永, 英男 諸井, 慶七郎 井上, 聡己 菊本, 克郎 田山, 準子 奥田, 孝雄 http://hdl.handle.net/10564/1771 2017-05-29T06:07:40Z 1993-10-30T15:00:00Z

タイトル: 最近6年間(1987年-1992年)の奈良県立医科大学麻酔科管理症例における緊急手術の推移 著者: 古家, 仁; 葛本, 直哉; 平井, 雅治; 北口, 勝康; 山上, 裕章; 下川, 充; 謝, 慶一; 梁, 宗哲; 長畑, 敏弘; 橋爪, 圭司; 松澤, 伸好; 橋本, 道代; 榮長, 登志; 二永, 英男; 諸井, 慶七郎; 井上, 聡己; 菊本, 克郎; 田山, 準子; 奥田, 孝雄 抄録: Emergency operations from 1987 to 1992 in N ara Medical University Hospital were analyzed. Annual total numbers of anesthetized patients were 2811 cases in 1987, 2843 cases in 1988, 2938 cases in 1989, 3154 cases in 1990, 3243 cases in 1991, and 3295 cases in 1992 respectively, in which annual numbers of emergency operations were 357 cases in 1987, 361 cases in 1988, 370 cases in 1989, 492 cases in 1990, 509 cases in 1991, and 513 cases in 1992. They were promptly increased after the establishment of the Department (Dpt.) of Emergency and Critical Care Medicine in 1990. The most frequent performed operations as emergency surgery were as follows : Caesarean section and ectopic pregnancy in Dpt. of Obstetrics and Gynecology ; appenditis and peritonitis in Dpt. of 1st Surgery ; hydrocephalus, intracerebral hematoma, and cerebral aneurysm in Dpt. of 2nd Surgery ; aortic aneurysm and pneumothorax in Dpt. of 3rd Surgery ; appenditis, peritionitis, subdural hematoma, intracerebral hematoma, and cerebral aneurysm in Dpt. of Emergency and Critical Care Medicine. On the initiation time of surgery, 38.9% of emergency cases were started between 12 noon and 4p.m.. Average anesthetic times were as follows : 316 min (Dpt. of 3rd Surgery), 250 min (Orthopedics), 241 min (Critical Care Medicine) and 237 min (2nd Surgery). Whenever surgeons propose an emergency case, anesthesiologist should not cancel their requirement for morbid patient care. Hence it should be defined the reasonable decision (indication, initiation time etc.), and rules for perforning emergency operation, such as adequate numbers of operation rooms with surgeons, anethesiologists, nurses, and paramedical staffs.

1993-10-30T15:00:00Z 平井, 宏明 http://hdl.handle.net/10564/1770 2017-05-29T06:07:40Z 1993-10-30T15:00:00Z

タイトル: 光学的方法による眼軸長測定法 著者: 平井, 宏明 抄録: In IOL power prediction, an error of axial length significantly affects the accuracy of implant power calculation. For the purpose of improving the accuracy of axial length measurement, a noncontact optical method for axial length measurement in cataract surgery was developed. Using a newly developed portable infrared autorefractometer (GR-M3) and a contact lens, the author measured refractive states of aphakia just before IOL implantation in 54 cases. Ten measurements could easily be taken within 2 minutes. Using the ray tracing technique and a portable computer, refractive errors were converted into axial length immediately. Then IOL power calculation and IOL implantation were performed. The data of axial length acquired by this method are compared with data obtained from the conventional ultrasonic method. Between them, good correlation was obtained (r=0.981). In 51 cases (94%), differences between the new method and the ultrasonic method were smaller than 0.35 mm. In 3 cases, differences were larger than 0.36 mm. In these cases, the axial length obtained with the ultrasonic measurements were shorter than results obtained with the optical method. The measured results were converted into calculated values based on ray tracing and were compared with refraction data after operation, revealing that the axial length acquired by the optical method was more accurately measured than by the ultrasonic method. This method may contribute greatly to measuring axial length at cataract surgery.

1993-10-30T15:00:00Z